The study aims at exploring effective and sustainable rodent controll interventions in the Mano River Region.
Specific objectives include:
- Estimate the human Lassa Seroprevelence by age and sex in six villages in the Bo District.
- Explore whether rodent elimination is promising, feasible and acceptable in the study sites.
- Examine the phylogeny of Lassa Virus in a transect from Freetown in Sierra Leone to Farannah in Guinea to enhance our understanding of Lassa Virus migration.
- To study air-borne transmission of Lassa Virus in houses.
- To evaluate the impact of the Ebola outbreak on people’s perception on Public Health interventions and zoonotic disease risks, and people’s relationship with rodents
Characterizing HIV Drug Resistance and co-infections in Sierra Leone: In collaboration with Case Western Reserve University in the United States of America.
- Perform a cross-sectional survey to assess the seroepidemiology and clinical features of HBV, HCV, HTLV and syphilis co-infection among HIV-infected sub groups in Sierra Leone.
- Characterize the modular epidemiology of HBV infection including HBV genotypes and mutations associated with drug resistance and vaccine escape mutants among HIV / HBV co infected patients in Sierra Leone.